"Frameshift" Example Sentences
1. Frameshift mutations can cause significant changes in amino acid sequence.
2. The insertion of an extra nucleotide can cause a frameshift mutation.
3. Frameshift errors in DNA replication can lead to genetic disorders.
4. The frameshift mutation in the CFTR gene can cause cystic fibrosis.
5. Frameshifts can be caused by DNA damage from carcinogens.
6. Frameshift mutations can lead to premature stop codons.
7. Policeman's helmet is a frameshift mutation in the plant Peloria.
8. The frequency of frameshift mutations is relatively low.
9. Ribosomal frameshifts can result in different protein products.
10. Frameshift errors can occur during transcription or translation.
11. The frameshift mutation in the CD45 gene can cause severe combined immunodeficiency disease.
12. Frameshifts are more likely to occur during DNA replication in regions of repetitive DNA.
13. Certain types of frameshift errors can be corrected by proofreading enzymes.
14. Frameshifts can also occur due to errors in RNA editing.
15. The severity of the effects of a frameshift mutation can vary depending on its location in the gene.
16. Some frameshift mutations can result in truncated or non-functional proteins.
17. Frameshift mutations have been implicated in a variety of genetic diseases.
18. Frameshifts can occur spontaneously or as a result of exposure to mutagenic agents.
19. Frameshift mutations are generally considered to be more detrimental than missense mutations.
20. The genetic code is read in triplets, and frameshift mutations can disrupt this reading frame.
21. Frameshift mutations can sometimes be beneficial, leading to the creation of novel protein functions.
22. Ribosomal frameshifting can be exploited by viruses to produce more proteins from a single transcript.
23. Frameshift mutations can occur in both protein-coding and non-coding regions of the genome.
24. Certain cancer treatments aim to induce frameshift mutations in tumor cells.
25. Frameshift mutations can also occur in mitochondrial DNA.
26. Frameshift errors can be identified through DNA sequencing or by analyzing protein products.
27. Frameshift mutations can cause genetic disorders such as Huntington's disease, Marfan syndrome, and Xeroderma pigmentosum.
28. The insertion or deletion of a single nucleotide can cause a frameshift.
29. Some frameshift mutations can be repaired by the mismatch repair system.
30. Frameshifts can be a potential mechanism for generating diversity in immune receptor genes.
Common Phases
1.
Frameshift mutations can alter the genetic code;
2.
Frameshift errors can have significant impacts on protein structure and function;
3.
Frameshift mutations can lead to genetic diseases;
4.
Frameshift mutations can occur spontaneously or be induced by mutagens;
5.
Frameshift mutations can result in premature stop codons and truncated proteins;
6.
Frameshifts can occur during DNA replication or RNA transcription;
7.
Frameshift mutations can be detected through genetic sequencing techniques.