Homozygous example sentences
Related (9): alleles, genotype, inheritance, recessive, dominant, phenotype, breeding, DNA, homozygote.
"Homozygous" Example Sentences
Common Phases
1. The homozygous genotype refers to having two identical alleles of a given gene, one inherited from each parent.
2. The homozygous mice showed a higher susceptibility to the disease.
3. Wild type mice are often homozygous for the normal allele of the gene of interest.
4. Heterozygous carriers have one normal and one mutated allele, while homozygotes have two copies of the mutated allele.
5. They used homozygous knockout mice that lack the gene for the receptor of interest.
6. The homozygous offspring received two copies of the mutant allele from their heterozygous parents.
7. All the plants with the mutant phenotype were homozygous for the recessive allele.
8. The researchers crossbred homozygous brown mice with homozygous white mice.
9. All the homozygous plants showed stunted growth and deformed leaves.
10. The researchers wanted to create a homozygous recessive strain of mice for the experiment.
11. Homozygous dominance occurs when both genes from the parents are dominant.
12. The homozygous recessive individuals produce offspring with the trait 100% of the time.
13. Homozygous advantage refers to a fitness advantage of organisms with two identical copies of a specific allele.
14. Most domesticated animals and plants are largely homozygous due to artificial selection by breeders.
15. Homozygous dominant individuals have a higher fitness than heterozygotes in some environments.
16. The model organism was chosen because it is easily made homozygous through inbreeding.
17. Homozygosity mapping is used to identify causative genes in individuals homozygous for a recessive disorder.
18. Homozygous deletions occur when both copies of a gene are deleted from a chromosome.
19. The researchers selected homozygous worms with the mutant phenotype for further study.
20. They used homozygous parent strains to generate heterozygous F1 offspring for mapping.
21. They performed genotyping to identify plants that were homozygous for the mutant allele.
22. They self-crossed the heterozygous plants to find homozygous individuals with the recessive trait.
23. Inbreeding leads to offspring that are more likely to be homozygous for specific gene variants.
24. They purified homozygous mutant cell lines by serial dilution and replating.
25. Homozygous advantage is often seen in environments with extreme or specialized conditions.
26. These traits often segregate in homozygous dominant and recessive forms in offspring.
27. Siblings of affected individuals are often carrier heterozygotes for the homozygous recessive disorder.
28. Homozygous mutants were isolated by selecting offspring with the recessive phenotype.
29. They identified regions of homozygosity in individuals with autosomal recessive conditions.
30. The homozygous state is often associated with deleterious phenotypes due to loss of function.
31. The experiment crossed homozygous round and homozygous wrinkled pea plants.
32. These organisms will give rise to homozygous offspring only when self-fertilized.
33. They screened populations to identify homozygous mutants with the desired phenotype.
34. Individuals with two different alleles are heterozygous, while those with identical alleles are homozygous.
35. The offspring had yellow flowers, indicating they were likely homozygous recessive.
36. The homozygous advantage hypothesis posits that higher genetic uniformity confers benefits.
37. The researchers selected seedlings with the mutant phenotype and selfed them to isolate homozygotes.
38. The data suggests a homozygous advantage in locally adapted populations.
39. Human populations show high levels of homozygosity due to genetic drift and inbreeding.
40. Inbreeding results in increased homozygosity and reduced heterozygosity.
41. Consanguineous marriages increase the probability of offspring being homozygous for rare recessive alleles.
42. The mutant alleles interact epistatically in homozygotes but not in heterozygotes.
43. They used a PCR based assay to verify homozygosity of the mutant allele in selected lines.
44. Homozygous individuals are often carriers of rare recessive disorders.
45. They isolated homozygous individuals through successive rounds of self-pollination.
46. Many desirable crop varieties have been selected to be largely homozygous.
47. They identified high frequency genotypes that appear to confer a homozygous advantage.
48. The homozygous advantage arises when heterozygotes suffer from disruptive interactions of alleles.
49. Homozygous losses of function mutations usually have the most severe phenotypes.
50. The growth advantage of homozygotes decreased at higher densities in the experiment.
51. Inbreeding reduces heterozygosity and increases the proportion of homozygous loci.
52. Hemizygosity refers to having only one copy of a gene on an allele in an otherwise homozygous organism.
53. Carriers are obligate heterozygotes who produce affected homozygous offspring.
54. Most pedigrees show an autosomal recessive inheritance pattern with homozygous affected individuals.
55. The trait is highly polygenic, with individual loci largely homozygous across individuals.
56. The homozygous state may confer increased fitness if one allele is particularly well adapted.
57. Related individuals are likely to share regions of homozygosity by descent.
58. They speculated that homozygous deletions cause loss of gene function and disease.
59. Consanguineous marriages increase the risk of offspring being homozygous for rare recessive alleles.
60. Loss of function mutations are typically only observed in the homozygous state.