"Japaconitine" Example Sentences
1. Japaconitine is an alkaloid found in the Aconitum plant.
2. The toxicity of japaconitine lies in its ability to activate sodium ion channels.
3. The presence of japaconitine in Chinese herbal medicines is of concern due to its potential toxicity.
4. Japaconitine poisoning can cause numbness and tingling in the mouth and extremities.
5. The effects of japaconitine on the cardiovascular system can be life-threatening.
6. Japaconitine is considered to be one of the most toxic aconitum alkaloids.
7. The pharmacological properties of japaconitine have been extensively studied in recent years.
8. Japaconitine alkaloids have been used for centuries in traditional Chinese medicine for their analgesic properties.
9. The neurotoxic effects of japaconitine include hyperactivity, convulsions, and respiratory failure.
10. Japaconitine poisoning is difficult to diagnose due to the lack of specific symptoms.
11. Japaconitine alkaloids can be extracted from the Aconitum plant using various methods.
12. The potency of japaconitine can vary depending on the species of Aconitum.
13. Japaconitine is known to interact with sodium ion channels, leading to depolarization and cellular damage.
14. The lethal dose of japaconitine in humans is estimated to be very low.
15. Japaconitine toxicity can be treated with supportive care and specific antidotes, if available.
16. Herbal medicines containing japaconitine are often sold online, despite being banned in many countries.
17. Japaconitine is sometimes called "wild aconite" due to its origin from the Aconitum plant.
18. The use of japaconitine as a poison dates back to ancient times.
19. The toxicity of japaconitine is due to its ability to interfere with nerve conduction and cardiac function.
20. Japaconitine poisoning is more common in rural areas where traditional medicine is still widely practiced.
21. Japaconitine belongs to a class of alkaloids known as aconitum toxins.
22. The toxic effects of japaconitine can be delayed, making diagnosis and treatment challenging.
23. Japaconitine is not approved for use in any pharmaceutical products due to its high toxicity.
24. The potential benefits of japaconitine alkaloids as pain relievers are outweighed by their toxicity.
25. Japaconitine is sometimes used in veterinary medicine as a sedative or an anesthetic.
26. Consumers should be wary of herbal medicines containing japaconitine, as they may be counterfeit or contaminated.
27. The chemical structure of japaconitine includes a bicyclic diterpene core.
28. Japaconitine can cause arrhythmias and cardiac arrest in severe cases of poisoning.
29. The mechanism of action of japaconitine involves opening of voltage-gated sodium ion channels.
30. Japaconitine can also cause gastrointestinal symptoms such as nausea, vomiting, and diarrhea.
Common Phases
1.
Japaconitine is a toxic compound;
2. The toxicity of
japaconitine is due to its effect on the nervous system;
3.
Japaconitine has been used historically as a poison;
4. The symptoms of
japaconitine poisoning include numbness, tingling, and muscle weakness;
5.
Japaconitine is found in a variety of plants, including aconite and monkshood.