"Keratinocytes" Example Sentences
1. Keratinocytes are the predominant cells found in the epidermis.
2. The production and differentiation of keratinocytes is necessary for the formation of the skin barrier.
3. UV radiation can damage the DNA in keratinocytes, leading to mutations and potential cancer development.
4. Keratinocytes in the stratum corneum are mostly dead and flattened, forming a protective layer over the skin.
5. Keratinocytes in the stratum basale are responsible for replenishing the epidermis through cell division.
6. The formation of cornified envelopes around keratinocytes is an essential part of the epidermal barrier function.
7. The extracellular matrix surrounding keratinocytes plays a critical role in regulating their behavior.
8. The differentiation of keratinocytes is regulated by the interplay between various signaling pathways.
9. Certain diseases and conditions can affect the proliferation and differentiation of keratinocytes in the skin.
10. Keratinocytes can release cytokines and other signaling molecules that can influence immune responses in the skin.
11. The interaction between keratinocytes, melanocytes, and Langerhans cells helps to protect the skin from UV damage and infection.
12. Hyperproliferation of keratinocytes can lead to conditions such as psoriasis and eczema.
13. Stem cells in the hair follicle can differentiate into keratinocytes, contributing to hair growth.
14. Immunohistochemistry can be used to identify and study different subsets of keratinocytes in the skin.
15. Keratinocyte-specific knockout mice have been used to investigate the role of various genes in skin development and function.
16. Mast cells can release histamine and other mediators that can influence the behavior of nearby keratinocytes.
17. The mechanical properties of keratinocytes can be modulated by changes in their cytoskeleton and adhesion molecules.
18. Keratinocyte-derived growth factors can stimulate the migration and proliferation of nearby fibroblasts and other cells.
19. Laser ablation can be used to selectively remove layers of keratinocytes from the skin, allowing for precise remodeling.
20. The expression of different keratin genes can be used to distinguish between different types of epithelial cells.
21. Ingrown hairs can result from the blockage of hair follicles by overlying keratinocytes or sebum.
22. Chronic exposure to irritants and allergens can cause inflammation and damage to keratinocytes in the skin.
23. Keratinocytes in hair bulbs undergo periodic cycles of proliferation and differentiation, leading to normal hair growth.
24. The formation of filaggrin by keratinocytes plays a role in the maintenance of skin hydration and pH balance.
25. Certain chemicals and drugs can cause toxic effects on keratinocytes, leading to cell death and tissue damage.
26. Keratinocytes can express a variety of toll-like receptors, which are involved in the recognition of microbial pathogens.
27. The organization and architecture of keratinocytes in the epidermis are crucial for their mechanical and functional properties.
28. Keratinocytes can interact with peripheral nerves in the skin, influencing sensory processing and pain perception.
29. The genetic and epigenetic regulation of keratinocyte behavior is an area of active research in dermatology.
30. Co-culture systems can be used to study the interactions between keratinocytes and other cell types in the skin.
Common Phases
1.
Keratinocytes comprise the majority of cells in the outer layer of the skin;
2. The main function of
keratinocytes is to produce a tough, protective protein called keratin;
3.
Keratinocytes also play a role in maintaining skin hydration and barrier function;
4. Abnormal keratinocyte growth can lead to skin conditions such as psoriasis and eczema;
5. Damage to
keratinocytes from sun exposure can increase the risk of skin cancer.