P53 example sentences

"P53" Example Sentences

1. p53 is a crucial tumor suppressor gene.
2. The p53 pathway is often disrupted in cancer.
3. Mutations in p53 are frequently observed in various cancers.
4. Researchers are studying the role of p53 in cancer development.
5. Dysfunctional p53 contributes to genomic instability.
6. p53 activation triggers cell cycle arrest.
7. p53 can induce apoptosis in damaged cells.
8. Understanding p53 is vital for cancer therapy.
9. Targeting p53 is a promising area of cancer research.
10. The activity of p53 is tightly regulated.
11. Many cancers evade p53-mediated apoptosis.
12. p53 plays a central role in DNA damage response.
13. Loss of p53 function promotes tumorigenesis.
14. Restoring p53 function is a therapeutic goal.
15. The p53 protein is a transcription factor.
16. p53 regulates the expression of many genes.
17. Mutations in p53 can lead to drug resistance.
18. Scientists are developing p53-activating drugs.
19. The p53 pathway is complex and multifaceted.
20. p53 is a guardian of the genome.
21. Aberrant p53 signaling contributes to metastasis.
22. p53 status is a prognostic marker in some cancers.
23. Targeting p53 with gene therapy is under investigation.
24. The role of p53 in aging is being explored.
25. p53 is involved in cellular senescence.
26. Defective p53 impairs DNA repair mechanisms.
27. p53 is a key regulator of cell fate.
28. Reactivation of p53 may enhance cancer treatment efficacy.
29. The p53 protein undergoes post-translational modifications.
30. p53 can induce cell cycle arrest at various checkpoints.
31. Disruption of p53 can lead to uncontrolled cell proliferation.
32. p53 interacts with numerous other proteins.
33. Research on p53 has advanced our understanding of cancer.
34. Future studies on p53 may lead to novel therapies.
35. The importance of p53 in cancer biology is undeniable.
36. We are still learning about the intricacies of p53.
37. p53 is a highly conserved protein.
38. The expression levels of p53 fluctuate dynamically.
39. p53-dependent apoptosis is a crucial defense against cancer.
40. Monitoring p53 status can help predict treatment response.
41. Studies on p53 are ongoing in many laboratories worldwide.
42. p53 is involved in regulating metabolic pathways.
43. Targeting p53 requires a multi-pronged approach.
44. The complexity of p53 makes it a challenging therapeutic target.
45. p53 plays a role in maintaining genomic stability.
46. p53 deficiency contributes to increased cancer risk.
47. Restoration of wild-type p53 function is a significant challenge.
48. Innovative strategies are needed to effectively target p53.
49. The study of p53 is fundamental to cancer research.
50. p53 remains a central focus in oncology.