Quinazolinone example sentences

Related (18): heterocyclic, nitrogen, benzene, ring, pharmacological, synthesis, derivatives, anticonvulsant, medication, bioactive, serotonin, receptor, antagonists, ligands, inhibitors, antidepressant, analgesic, anxiolytic.

"Quinazolinone" Example Sentences

1. The pharmacological activity of quinazolinone derivatives has been extensively studied.
2. Quinazolinone-based compounds are used as new anticancer drugs.
3. The synthesis of quinazolinone is a critical step in drug development.
4. Researchers are interested in the role of quinazolinone derivatives in neurological disorders.
5. Quinazolinone ring structures play a vital role in drug discovery and development.
6. The antifungal activity of quinazolinone derivatives has been demonstrated in several studies.
7. The discovery of CXCR4 inhibitors based on quinazolinone scaffolds has been reported.
8. Quinazolinone analogs have shown potential as antitumor agents in vitro and in vivo.
9. The synthesis of 2-aminobenzimidazole-4,7-dione scaffold is similar to that of quinazolinone.
10. The binding affinity of quinazolinone derivatives to their target receptor has been determined.
11. A QSAR study was carried out to investigate the structure-activity relationship of quinazolinone derivatives.
12. Quinazolinone-based inhibitors of protein kinase CK2 have been developed as anticancer agents.
13. A novel quinazolinone compound with antibacterial activity was synthesized and evaluated.
14. The crystal structure of a quinazolinone derivative complexed with its target protein has been determined.
15. Several quinazolinone derivatives have shown excellent antidepressant activity in preclinical trials.
16. The spectroscopic properties of quinazolinone and its derivatives have been investigated extensively.
17. Quinazolinone derivatives are widely used as intermediates in the synthesis of pharmaceuticals.
18. The toxicity profile of quinazolinone derivatives has been evaluated to determine their safety.
19. A computational study was performed to explore the binding mode of quinazolinone analogs to their target protein.
20. The synthesis of quinazolinone derivatives can be achieved by various methods, including Hantzsch reaction and microwave-assisted synthesis.
21. The antiviral activity of quinazolinone derivatives has been reported for several viruses.
22. Quinazolinone derivatives containing a nitrogen mustard moiety have been developed as potential anticancer agents.
23. The pharmacokinetic properties of quinazolinone derivatives have been studied in animals and humans.
24. A molecular docking study was performed to investigate the interaction of quinazolinone derivatives with their target receptor.
25. The use of quinazolinone-based compounds in drug delivery systems has been proposed.
26. Several quinazolinone derivatives have been identified as potent inhibitors of cyclic nucleotide phosphodiesterase (PDE).
27. The effect of structural modifications on the activity of quinazolinone derivatives has been investigated.
28. Quinazolinone-based compounds have been evaluated as potential therapeutic agents for Alzheimer's disease.
29. A green chemistry approach for the synthesis of quinazolinone derivatives has been proposed.
30. Quinazolinone derivatives have shown therapeutic potential in a wide range of diseases, including cancer, infectious diseases, and neurological disorders.

Common Phases

1. Quinazolinone is a heterocyclic compound;
2. Quinazolinone derivatives have therapeutic potential;
3. Quinazolinone-based inhibitors have been developed for various diseases;
4. Quinazolinone-containing molecules are widely used in drug discovery;
5. Quinazolinone alkaloids have been found in certain plants.

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