"Rotarod" Example Sentences
1. The rotarod is a piece of laboratory equipment used to assess motor coordination and balance in animals.
2. The researchers measured the time the mice were able to stay on the rotarod during the experiment.
3. The rotarod task proved to be a reliable indicator of the effects of the drug on motor function.
4. The rats underwent daily training on the rotarod before being tested under different conditions.
5. The study found that female mice performed better on the rotarod than males.
6. The rotarod test is commonly used in preclinical drug development to evaluate potential therapeutic compounds.
7. The rotarod apparatus is fitted with a rotating spindle on which the animals are placed.
8. The results of the rotarod test indicated that the experimental group exhibited significant deficits in motor coordination compared to the control group.
9. The rotarod task is useful for assessing the effects of genetic mutations on motor function.
10. The researchers analyzed the speed of the rotarod spindle to determine the optimal speed for the task.
11. The mice were subjected to multiple trials on the rotarod to determine the most consistent results.
12. The rotarod performance of the animals was used as a predictor of their overall motor ability.
13. The test protocol for the rotarod included a warm-up period before the actual trial began.
14. The mice were trained to run on the rotarod by gradually increasing the speed of the spindle.
15. The rotarod is a commonly used method for studying Parkinson's disease and other movement disorders.
16. The researchers hypothesized that the rats would exhibit improved motor coordination skills after being trained on the rotarod.
17. The use of the rotarod improved the sensitivity of the behavioral tests used in the study.
18. The mice were categorized based on their performance on the rotarod, with the top performers being selected for further investigation.
19. The rotarod task was combined with other behavioral tests to create a comprehensive picture of the animals' abilities.
20. The rotarod is often used in toxicology studies to assess the effects of chemical exposure on motor coordination.
21. The researchers tested the effects of different doses of the drug on the mice's performance on the rotarod.
22. The rotarod task was modified to include different surface textures to assess the animals' balance under different conditions.
23. The study found that the age of the animals had a significant impact on their performance on the rotarod.
24. The rotarod test has been adapted for use in non-human primates to study the effects of brain damage on motor function.
25. The mice were sacrificed after the rotarod trials to allow for further analysis of their brains.
26. The rotarod can be used for both acute and chronic studies of motor function in animals.
27. The study compared the performance of genetically modified mice on the rotarod to that of wild-type mice.
28. The rotarod was used to assess the effects of a new therapeutic compound on the motor function of rats with spinal cord injuries.
29. The study found that the rotarod was a reliable indicator of changes in motor function caused by aging.
30. The use of the rotarod allowed the researchers to identify specific brain regions involved in motor coordination.
Common Phases
- Start the
rotarod;
- Adjust the speed;
- Begin the trial;
- Place the animal on the rod;
- Record the latency to fall;
- Stop the
rotarod;
- Clean the rod for the next trial;
- Repeat the procedure for multiple trials;
- Analyze the results.