Ubiquitylated example sentences

"Ubiquitylated" Example Sentences

1. The ubiquitylated protein was rapidly degraded by the proteasome.
2. Researchers found that the ubiquitylated protein showed altered cellular localization.
3. Ubiquitylated histone H2B plays a crucial role in gene transcription regulation.
4. The study demonstrated a correlation between disease progression and the level of ubiquitylated proteins.
5. Ubiquitylated proteins are often targeted for lysosomal degradation.
6. He discovered a novel E3 ligase responsible for ubiquitylating a specific target protein.
7. They observed a significant increase in ubiquitylated proteins under stress conditions.
8. The experiment showed that the ubiquitylated receptor was internalized.
9. Ubiquitylation, the process of adding ubiquitin, often leads to protein degradation.
10. Misregulation of ubiquitylation is implicated in several diseases.
11. The mechanism by which this protein is ubiquitylated remains unclear.
12. Further research is needed to elucidate the role of ubiquitylated proteins in this pathway.
13. This newly identified enzyme specifically ubiquitylates this particular substrate.
14. The ubiquitylated form of the protein was less active.
15. Ubiquitylated proteins can be identified using specific antibodies.
16. The cell's response to DNA damage includes the ubiquitylation of several proteins.
17. It is hypothesized that this protein is ubiquitylated in a specific cellular compartment.
18. The ubiquitylated protein was found to interact with other signaling molecules.
19. They demonstrated that the ubiquitylation site is essential for protein function.
20. Ubiquitylation is a crucial post-translational modification.
21. The level of ubiquitylated p53 correlates with cancer severity.
22. Unexpectedly, the ubiquitylated protein was found to be stabilized.
23. It's crucial to understand how proteins are ubiquitylated and degraded.
24. The ubiquitylated substrate was subsequently processed by the proteasome.
25. This finding suggests a novel role for ubiquitylation in cell cycle regulation.
26. Analysis revealed that the ubiquitylated protein was predominantly localized to the nucleus.
27. We propose that ubiquitylation regulates the activity of this protein.
28. The ubiquitylated protein underwent a conformational change.
29. Ubiquitylation-mediated degradation is a key cellular process.
30. The researchers confirmed that the protein was indeed ubiquitylated.
31. This study highlights the importance of ubiquitylation in cellular homeostasis.
32. Determining the specific E3 ligase that ubiquitylates this protein is essential.
33. The ubiquitylated form of the protein was more susceptible to degradation.
34. Ubiquitylation is a complex and dynamic process.
35. They are investigating the role of ubiquitylated proteins in immune responses.
36. The ubiquitylation status of the protein was altered by the drug treatment.
37. Ubiquitylated proteins are frequently involved in signal transduction cascades.
38. Their results indicate that ubiquitylation negatively regulates the protein’s function.
39. The precise timing of ubiquitylation is critical for proper cellular function.
40. How this protein is ubiquitylated under physiological conditions is still unclear.
41. This suggests a possible role for ubiquitylation in this disease pathway.
42. Further investigation into the ubiquitylation of this protein is warranted.
43. The ubiquitylated protein showed impaired binding affinity.
44. The effect of ubiquitylation on protein stability varies greatly.
45. Several inhibitors of ubiquitylation are currently under development.
46. We observed that the ubiquitylated protein was sequestered in inclusion bodies.
47. The researchers used a mass spectrometry approach to identify ubiquitylated proteins.
48. Ubiquitylation plays a multifaceted role in various cellular processes.
49. This novel finding provides insight into the regulation of ubiquitylation.
50. The ubiquitylated protein's half-life was significantly shortened.