"Anticodon" Example Sentences
1. The anticodon region of the tRNA molecule pairs with the codon region of the mRNA during translation.
2. The three nucleotides of the anticodon determine the amino acid that will be inserted into the growing protein chain.
3. Mutations in the anticodon can lead to errors in the protein synthesis process.
4. The anticodon loop is a crucial structural element of tRNA.
5. Different tRNAs have different anticodons, allowing them to bind to different mRNA sequences.
6. The wobble position of the anticodon allows for flexibility in base-pairing.
7. The binding of the anticodon to the codon is stabilized by hydrogen bonds.
8. Aminoacyl-tRNA synthetases are enzymes that attach the correct amino acid to the appropriate tRNA anticodon.
9. The Ribosome recognizes the anticodon and facilitates the formation of the peptide bond.
10. The anticodon is located on the loop of the tRNA molecule opposite the amino acid attachment site.
11. The sequence of the anticodon is complementary to the codon sequence on the mRNA.
12. Hydrogen bonding between the anticodon and the codon helps to maintain the correct reading frame.
13. The identity of the amino acid carried by the tRNA is determined by the anticodon sequence.
14. The vast majority of tRNA genes encode multiple tRNA molecules with different anticodons.
15. In some organisms, there are two or more tRNAs with the same anticodon but different amino acids.
16. The ribosome moves along the mRNA in the 5' to 3' direction, while the anticodon reads in the opposite direction.
17. The tRNA anticodon loop can undergo conformational changes during translation.
18. Prokaryotes have a different anticodon usage bias than eukaryotes.
19. A mutation that changes the anticodon sequence can lead to misreading of the genetic code.
20. In some bacteria, a modified nucleotide in the anticodon can enhance translation efficiency.
21. The ribosome recognizes the anticodon and positions the tRNA in the A site for peptide bond formation.
22. The anticodon stem-loop structure is important for tRNA stability and function.
23. Some viruses use rare codons in their genes to limit the availability of tRNAs with the corresponding anticodon.
24. Non-coding RNA molecules, such as RNA interference and microRNA, can base-pair with mRNAs and hinder the accessibility of the ribosome to the codon-anticodon site.
25. The recognition of the codon-anticodon interaction is a key aspect of proofreading by the ribosome.
26. The anticodon is a conserved feature of all known tRNA molecules.
27. In some cases, the same tRNA molecule can recognize two or more different codons with a partially overlapping anticodon.
28. The structure of the anticodon loop can play a role in determining the accuracy of codon recognition.
29. In extreme conditions such as high salinity and temperature, the modification of tRNA anticodon nucleotides can improve translation efficiency.
30. A genetic code expansion system that incorporates non-natural amino acids into proteins requires the creation of new tRNAs with anticodons that are orthogonal to the natural ones.
Common Phases
1. The
anticodon is a region of tRNA responsible for base-pairing with the codon on mRNA;
2. The specificity of the
anticodon dictates which amino acid is attached to the tRNA;
3. Aminoacyl-tRNA synthetase enzymes ensure that the correct amino acid is attached to the appropriate
anticodon;
4. Mutations in the
anticodon can result in mispairing with codons and errors in protein synthesis;
5. The binding affinity between the
anticodon and codon influences the speed and accuracy of translation;
6. The wobble hypothesis suggests that some tRNAs can base-pair with multiple codons due to flexibility within the
anticodon region;
7. Modification of the
anticodon, such as methylation, can alter the function and specificity of tRNAs.