"Globotriosylceramide" Example Sentences
1. Globotriosylceramide is a type of glycosphingolipid found in many different tissues.
2. The presence of globotriosylceramide is associated with certain genetic disorders.
3. Some bacteria can synthesize globotriosylceramide as a way to invade host cells.
4. Researchers are studying how globotriosylceramide interacts with other molecules in the body.
5. The structure of globotriosylceramide is quite complex, with multiple sugar residues.
6. Mutations in the enzyme responsible for making globotriosylceramide can lead to disease.
7. One way to detect globotriosylceramide in cells is to use antibodies that specifically bind to it.
8. Globotriosylceramide is often referred to by its abbreviated name, Gb3.
9. Certain toxins produced by bacteria can target globotriosylceramide on the surface of cells.
10. Some cancer cells express high levels of globotriosylceramide, which may be a target for therapy.
11. Synthetic versions of globotriosylceramide can be used to study its biological effects in vitro.
12. The function of globotriosylceramide in healthy cells is not well-understood.
13. Some scientists hypothesize that globotriosylceramide may play a role in cell signaling.
14. A rare but serious condition called Fabry disease is caused by a deficiency of an enzyme that breaks down globotriosylceramide.
15. Lipid rafts, specialized regions of the cell membrane, often contain high levels of globotriosylceramide.
16. Researchers are investigating whether blocking the production of globotriosylceramide could be a potential treatment for some diseases.
17. A method called thin layer chromatography can be used to separate globotriosylceramide from other lipids.
18. The molecular weight of globotriosylceramide is approximately 1,100 Da.
19. High levels of globotriosylceramide have been implicated in the development of atherosclerosis.
20. Certain viruses can use globotriosylceramide as a receptor to enter cells.
21. Mutations in the gene that codes for the globotriosylceramide synthase enzyme have been linked to some forms of neurodegenerative disease.
22. The crystal structure of globotriosylceramide has been determined using X-ray crystallography.
23. The role of globotriosylceramide in inflammatory processes is an active area of research.
24. Enzymes that can cleave off sugar residues from globotriosylceramide have been identified.
25. Some researchers are investigating whether globotriosylceramide could be used as a biomarker for certain diseases.
26. The synthesis of globotriosylceramide occurs in the Golgi apparatus of cells.
27. In some cases, blocking the function of globotriosylceramide can inhibit the growth of cancer cells.
28. Mutations in the gene for globotriosylceramide synthase can also lead to defects in the development of certain cell types.
29. There are several different isoforms of globotriosylceramide found in different tissues.
30. The crystal structure of globotriosylceramide has been used to design drugs that target it.
31. Research on globotriosylceramide has implications for the development of treatments for both genetic and infectious diseases.
32. The distribution of globotriosylceramide in different tissues varies depending on the species.
33. Some types of bacteria use a toxin that binds to globotriosylceramide to cause disease.
34. Glycosphingolipids like globotriosylceramide are important in processes like cell-cell recognition and signaling.
35. Studies have suggested that globotriosylceramide may play a role in the pathogenesis of certain autoimmune diseases.
36. Some studies have shown that globotriosylceramide can interact with proteins involved in immune responses.
37. The levels of globotriosylceramide in tissues can be affected by environmental factors like diet.
38. Researchers have found that globotriosylceramide can modulate the activity of certain ion channels in the cell membrane.
39. The interaction between globotriosylceramide and other molecules in the cell membrane can influence its function and signaling properties.
40. Mutations in the gene encoding globotriosylceramide synthase have been associated with a number of different neurological disorders.
Common Phases
1.
Globotriosylceramide is a glycosphingolipid found on the membrane of certain cell types;
2. The presence of
globotriosylceramide on the surface of cells has been linked to various diseases;
3. Infections caused by Escherichia coli strains that produce Shiga toxin are known to bind to
globotriosylceramide on host cells;
4.
Globotriosylceramide is a potential target for cancer therapy due to its overexpression on cancer cells;
5. The metabolism of
globotriosylceramide has been implicated in the development of insulin resistance in obese individuals;
6. Blocking the biosynthesis or function of
globotriosylceramide has been shown to have therapeutic potential in various diseases.