Glucuronide example sentences

"Glucuronide" Example Sentences

1. The liver processes many drugs by forming their glucuronide conjugates.
2. Glucuronide conjugation is a major pathway for drug metabolism.
3. Analysis revealed high levels of morphine-glucuronide in the patient's sample.
4. The study investigated the pharmacokinetics of the glucuronide metabolite.
5. Formation of a glucuronide can increase the water solubility of a compound.
6. Is the glucuronide of this compound pharmacologically active?
7. Researchers explored alternative pathways besides glucuronide conjugation.
8. Excretion of the glucuronide occurs primarily through the kidneys.
9. Glucuronide conjugation is an important detoxification mechanism.
10. The glucuronide conjugate was identified using mass spectrometry.
11. Measuring glucuronide levels can help monitor drug exposure.
12. Some glucuronides can be biologically active themselves.
13. The rate of glucuronide formation can vary significantly between individuals.
14. Genetic factors influence the efficiency of glucuronide conjugation.
15. Enzyme inhibition can affect the production of glucuronide metabolites.
16. This drug is extensively metabolized to its glucuronide form.
17. The presence of this glucuronide is a marker of exposure to the parent compound.
18. Further research is needed to understand the role of glucuronide in this disease.
19. Glucuronide formation is a phase II detoxification reaction.
20. The glucuronide metabolite was found to be less toxic than the parent compound.
21. We observed an increase in glucuronide excretion following drug administration.
22. What is the half-life of the glucuronide metabolite?
23. The study compared the levels of parent compound and its glucuronide.
24. How does the formation of glucuronide affect drug efficacy?
25. The glucuronide pathway is a crucial element in drug metabolism.
26. Glucuronide hydrolysis can occur under certain conditions.
27. The concentration of the glucuronide was below the limit of detection.
28. This method allows for the quantification of both parent compound and its glucuronide.
29. Many endogenous substances also undergo glucuronide conjugation.
30. The glucuronide pathway is saturable at high concentrations of substrate.
31. Deficiencies in glucuronide conjugation enzymes can lead to health problems.
32. Inhibition of glucuronide formation can increase drug toxicity.
33. Understanding glucuronide metabolism is crucial in drug development.
34. The glucuronide pathway is less efficient in newborns.
35. This glucuronide metabolite exhibits enterohepatic recirculation.
36. Are there any specific interactions between the drug and its glucuronide?
37. The glucuronide conjugate was purified using high-performance liquid chromatography.
38. The formation of glucuronide helps to eliminate xenobiotics from the body.
39. The glucuronide pathway contributes significantly to drug clearance.
40. We identified a novel glucuronide metabolite in this study.
41. The clinical significance of this glucuronide is unclear.
42. This drug's primary metabolite is a glucuronide.
43. Glucuronide conjugation is a common phase II metabolic reaction.
44. Analysis showed a significant increase in glucuronide levels after treatment.
45. The glucuronide metabolite was stable under the assay conditions.
46. Glucuronide conjugation can affect the pharmacodynamics of a drug.
47. The study evaluated the effect of age on glucuronide formation.
48. The research focused on the enzymatic mechanisms of glucuronide synthesis.
49. Elevated glucuronide levels may indicate liver dysfunction.
50. Further research is needed to fully elucidate the role of glucuronide in this process.

Common Phases

1. Glucuronide conjugation pathway
2. Bilirubin glucuronide
3. Glucuronide metabolites
4. Phase II glucuronidation
5. Glucuronide formation
6. Steroid glucuronides
7. Glucuronide hydrolysis
8. Increased glucuronide excretion
9. Serum glucuronide levels
10. Glucuronide-based drug conjugates
11. Glucuronide production
12. Glucuronide analysis
13. UDP-glucuronosyltransferase (UGT) glucuronide transfer
14. Excretion of glucuronides
15. Glucuronide detection
16. Pharmacokinetic glucuronide profile
17. Glucuronide conjugates of xenobiotics
18. Glucuronide quantification
19. Inherited glucuronide deficiency
20. Glucuronide synthesis
21. Glucuronide and drug metabolism
22. Glucuronide pathway impairment