"Hydroxylate" Example Sentences
1. The enzyme can hydroxylate phenylalanine to produce tyrosine.
2. In the presence of iron salts, the catalyst can hydroxylate benzoic acid.
3. The compound can be hydroxylated by adding potassium hydroxide to the reaction mixture.
4. The addition of oxygen and hydrogen peroxide to the reaction mixture allowed the enzyme to hydroxylate the substrate.
5. The hydroxylated product was isolated by column chromatography.
6. The molecule can be hydroxylated at multiple positions, leading to a complex mixture of products.
7. The reaction conditions were optimized to selectively hydroxylate the desired aromatic compound.
8. It is important to control the degree of hydroxylation of the final product.
9. The newly synthesized compound was characterized by NMR and showed hydroxylation at the para position.
10. The hydroxylation of alkenes is a common reaction in organic chemistry.
11. The enzyme responsible for hydroxylation is found in the liver.
12. The hydroxylated derivative of the drug has improved solubility, making it a more effective treatment option.
13. The hydroxylation of the substrate occurs through a radical mechanism.
14. The presence of a strong base is necessary to induce hydroxylation in this reaction.
15. The hydroxylation step is followed by a reduction to create the final product.
16. The hydroxylated intermediate can react with other species in the reaction mixture.
17. The hydroxylation of the amino acid leads to a change in its physical and chemical properties.
18. The product was identified by its characteristic mass spectra and NMR data, which confirmed hydroxylation.
19. A number of enzymes can hydroxylate organic compounds, including cytochrome P450.
20. Hydroxylation can occur under mild reaction conditions, making it a useful synthetic tool.
21. The hydroxylation of certain compounds can lead to the formation of toxic metabolites.
22. The degree of hydroxylation can affect the bioactivity of certain compounds.
23. The reaction rate of hydroxylation can be increased by increasing the temperature and pressure in the reaction vessel.
24. A specific hydroxylase enzyme is required to catalyze the hydroxylation of certain compounds.
25. The mechanism of hydroxylation involves the transfer of a hydroxyl group from a donor molecule to a substrate.
26. Hydroxylation can be used to functionalize biomolecules and create synthetic materials with unique properties.
27. The hydroxylation step can be difficult to control and may require multiple reaction steps to accomplish.
28. The hydroxyl group in hydroxylated compounds confers unique physicochemical properties and can be used for further chemical modification.
29. The addition of a Lewis acid can increase the rate of hydroxylation in certain reactions.
30. Hydroxylation of alkyl chains can lead to improved solubility and bioavailability of certain compounds.
Common Phases
1. They
hydroxylate the substrate using a catalytic enzyme;
2. In order to
hydroxylate the chemical compound, a source of oxygen is necessary;
3. The process of hydroxylation involves adding a hydroxyl group to a molecule;
4. Researchers have been able to
hydroxylate a wide range of organic compounds;
5. The ability to
hydroxylate certain compounds is important for drug metabolism and synthesis.