"Hydroxylations" Example Sentences
1. The hydroxylations of the steroid backbone greatly influence their biological activity.
2. The presence of hydroxylations on the phenylalanine molecule increases its solubility in polar solvents.
3. The hydroxylations of certain fatty acids can lead to the formation of pro-inflammatory mediators.
4. The degree of hydroxylation of a protein can affect its conformation and stability.
5. The hydroxylations of plant compounds are often catalyzed by cytochrome P450 enzymes.
6. The hydroxylation of vitamin D in the liver is a crucial step in its activation.
7. The hydroxylations of amino acids can contribute to the formation of reactive oxygen species.
8. The hydroxylation of tryptophan is an important step in the synthesis of serotonin.
9. The hydroxylation of tyrosine is a critical step in the biosynthesis of catecholamines.
10. The hydroxylation of proline is required for the proper folding of certain proteins.
11. The hydroxylation of lysine residues in collagen is essential for its stability and function.
12. The hydroxylation of histidine can affect its ability to act as a buffer in biological systems.
13. The selective hydroxylation of alkanes is a challenging area of research in organic chemistry.
14. The hydroxylation of steroids can drastically alter their pharmacokinetic properties.
15. The stereochemistry of hydroxylations can have a significant impact on the biological activity of a molecule.
16. The hydroxylation of polyunsaturated fatty acids can lead to the formation of potent anti-inflammatory mediators.
17. The hydroxylation of benzoic acid is a key step in the biosynthesis of salicylic acid.
18. The hydroxylation of certain xenobiotics can increase their water solubility and facilitate their excretion.
19. The hydroxylation of amino acids can occur through both enzymatic and non-enzymatic pathways.
20. The hydroxylation of heme is an important step in the synthesis of cytochromes and other heme-containing proteins.
21. The extent of hydroxylation of a drug molecule can influence its metabolism and clearance from the body.
22. The hydroxylations of certain flavonoids can impart antioxidant properties on these compounds.
23. The hydroxylation of pyridoxine is a necessary step in the biosynthesis of pyridoxal-5'-phosphate, an important coenzyme.
24. The hydroxylation of fatty acids can lead to the formation of molecules with diverse physiological functions.
25. The hydroxylation of certain amino acids can result in the formation of toxic metabolites.
26. The hydroxylation of certain neurotransmitters can modulate their activity at the synaptic cleft.
27. The hydroxylation of dopamine is a key step in the biosynthesis of norepinephrine and epinephrine.
28. The hydroxylation of certain neurotransmitters can lead to the formation of reactive oxygen species and oxidative stress.
29. The hydroxylations of certain plant compounds can create bitter or astringent flavors in food and beverages.
30. The selective hydroxylation of steroids is a common strategy in the development of drugs for metabolic and inflammatory disorders.
Common Phases
1. Hydroxylation is a type of chemical reaction;
2. It involves the addition of a hydroxyl group (-OH) to a molecule;
3. Hydroxylation plays a critical role in various biological processes;
4. It is commonly used to activate or deactivate drugs in the body;
5. The hydroxyl group can increase the water solubility of a molecule;
6. Hydroxylation can also alter the stability and reactivity of a molecule;
7. Some enzymes require hydroxylation as part of their mechanism;
8. Hydroxylation can occur at different positions within a molecule;
9. It is a key step in the biosynthesis of many natural products;
10. Hydroxylation can be carried out by various enzymes and chemical reagents.