"Myosins" Example Sentences
1. Myosins are a group of proteins that play a crucial role in muscle contraction.
2. The function of myosins is to generate movement by interacting with actin filaments.
3. There are several types of myosins in different organisms, but they all share a similar structure and function.
4. Myosins are ATP-powered motors that move along actin filaments by using the energy from hydrolysis of ATP.
5. Mutations in myosin genes can lead to various muscular disorders, such as hypertrophic cardiomyopathy.
6. One of the most studied myosins is myosin II, which is responsible for generating force and movement in skeletal muscles.
7. Myosins have been found in many other cell types besides muscle cells, demonstrating their versatility and importance in cellular processes.
8. Myosins are often associated with the formation of membrane protrusions, like the filopodia and lamellipodia that cells use for movement and sensing.
9. The ability of myosins to move along actin filaments is regulated by several mechanisms, including phosphorylation and binding to other proteins.
10. Some myosins, like myosin X, have a unique tail domain that allows them to bind to specific cargoes and transport them along actin filaments.
11. Myosins can also interact with other cytoskeletal elements, such as microtubules and intermediate filaments, to coordinate their functions.
12. The presence of myosins in non-muscle cells has been linked to various phenomena, such as cell division, cytokinesis, and vesicle trafficking.
13. Myosins are part of a larger superfamily of ATPases, including kinesins and dyneins, that are involved in intracellular transport and motility.
14. One of the most striking features of myosins is their ability to work in teams and generate coherent movement, like in the beating of cilia and flagella.
15. The diversity of myosins in different organisms and cell types suggests a complex evolution and adaptation to different physiological needs.
16. Myosins have been implicated in several diseases, including cancer, heart failure, and neurodegenerative disorders.
17. The molecular mechanisms of myosin activity are still being investigated, with new studies revealing unexpected functions and interactions.
18. The structure of myosins has been elucidated through X-ray crystallography and cryo-electron microscopy, providing insights into their mechanism and regulation.
19. The energy-efficient movement of myosins has inspired the development of bio-inspired robots and actuators.
20. Some organisms, like the amoeba Dictyostelium, rely on myosins for their social behavior and multicellular aggregation.
21. Myosins are involved in various sensory processes, such as the movement of hair cells in the inner ear and the touch response of neurons.
22. The study of myosins has led to the development of new drugs and therapies for muscle diseases and other conditions.
23. Myosins have unique mechanical properties that allow them to generate force and tension in cells, while minimizing energy consumption.
24. The use of myosin as a molecular motor in nanotechnology has opened up new avenues for drug delivery, sensing, and computation.
25. The coordination of myosin activity with other signaling pathways is critical for the proper functioning of cells and tissues.
26. Myosins can generate both contracting and protrusive forces, depending on the context and location in the cell.
27. Myosins are involved in several steps of embryonic development, such as gastrulation and neurulation in vertebrates.
28. The regulation of myosin activity is a complex process that involves multiple binding sites and interactions with other proteins.
29. The discovery of myosin VI, a reverse-direction motor, challenged the traditional view of myosins as unidirectional.
30. Myosins are a paradigm for studying protein structure-function relationships, with many open questions and opportunities for discovery.
Common Phases
1.
Myosins are motor proteins;
2.
Myosins are responsible for muscle contraction;
3.
Myosins use energy from ATP to move along actin filaments;
4.
Myosins are essential for cell division;
5.
Myosins play a critical role in transporting cargo within cells.