"Pepsinogens" Example Sentences
1. Pepsinogens are zymogens that are synthesized and secreted by the chief cells of the stomach.
2. The activation of pepsinogens requires the acidic pH of the stomach.
3. In the presence of hydrochloric acid, pepsinogens are converted into their active forms, pepsins.
4. The primary function of pepsinogens is to aid in the digestion of proteins.
5. Pepsinogens are secreted in response to the hormone gastrin.
6. The production of pepsinogens is regulated by neural and hormonal signals.
7. Pepsinogens are stored in the cytoplasm of chief cells in an inactive state.
8. The secretion of pepsinogens is enhanced by the parasympathetic nervous system.
9. Pepsinogens can be activated by other proteases, such as trypsin and chymotrypsin.
10. Elevated levels of pepsinogens may indicate an increased risk of gastric cancer.
11. Pepsinogens are part of the gastric juice that is secreted into the stomach.
12. The concentration of pepsinogens in the plasma can be used to assess the degree of gastric mucosal damage.
13. Infants produce more pepsinogens than adults due to their high protein intake.
14. The secretion of pepsinogens is inhibited by antacids and proton pump inhibitors.
15. The levels of circulating pepsinogens are influenced by genetic and environmental factors.
16. Pepsinogens are synthesized as inactive precursors to prevent self-digestion of the stomach.
17. The detection of pepsinogens in the stool can be used as a non-invasive test for gastric disease.
18. Pepsinogens are converted into pepsins by the removal of peptide fragments.
19. The synthesis of pepsinogens is upregulated in response to chronic stress.
20. The concentration of pepsinogens in the gastric juice increases during feeding.
21. Pepsinogens are cleaved by enzymes called pepsinogenases.
22. The secretion of pepsinogens is downregulated in response to alkaline solutions.
23. Pepsinogens are activated by the low pH of the gastric lumen.
24. The levels of pepsinogens in the gastric juice can be monitored during endoscopy.
25. Pepsinogens are used as markers of gastric function in clinical studies.
26. The secretion of pepsinogens is stimulated by histamine and acetylcholine.
27. The cleavage of pepsinogens involves the breakage of peptide bonds at specific sites.
28. Pepsinogens are delivered to the stomach via the bloodstream.
29. The function of pepsinogens can be impaired by diseases such as atrophic gastritis.
30. Pepsinogens are produced by the chief cells in response to neural and hormonal signals.
Common Phases
1.
Pepsinogens are inactive precursors of pepsin;
2. They are secreted by the chief cells of the gastric glands;
3.
Pepsinogens are activated by the presence of hydrochloric acid in the stomach;
4. This activation results in the production of pepsin which aids in protein digestion;
5. The secretion of
pepsinogens can be inhibited by certain medications and medical conditions.