"Tyrosinase" Example Sentences
1. The production of melanin is dependent on the activity of tyrosinase.
2. Tyrosinase is an important enzyme involved in the synthesis of melanin.
3. Mutations in the tyrosinase gene can cause albinism.
4. Tyrosinase activity is often used as a marker for melanoma progression.
5. The tyrosinase enzyme is found in melanocytes in the skin.
6. Tyrosinase inhibitors are used in cosmetic products to lighten skin tone.
7. The presence of tyrosinase is essential for melanin production in the eyes.
8. Tyrosinase is inhibited by certain drugs and chemicals, which can lead to skin lightening.
9. An absence of tyrosinase activity in melanocytes results in a lack of pigment production.
10. The tyrosinase enzyme catalyzes the conversion of tyrosine into dopaquinone.
11. The expression of tyrosinase in melanoma cells can have prognostic implications.
12. Tyrosinase plays a critical role in the development of pigment in the hair follicles.
13. Certain foods and supplements can increase tyrosinase activity in the body.
14. Tyrosinase-positive melanoma cells are often more aggressive than those without the enzyme.
15. Tyrosinase-deficient mice are commonly used in research to study melanocyte biology.
16. Anti-tyrosinase agents have been investigated as potential treatments for hyperpigmentation disorders.
17. Tyrosinase expression is regulated by a complex network of genetic and environmental factors.
18. The catalytic mechanism of tyrosinase involves the formation of a copper-oxygen intermediate.
19. Tyrosinase assays can be used to measure the enzyme activity in various tissues.
20. The tyrosinase enzyme is highly conserved across different species.
21. Tyrosinase-related protein 1 (TRP-1) is a closely related enzyme to tyrosinase.
22. The tyrosinase gene is located on chromosome 11 in humans.
23. The activity of tyrosinase is inhibited by low pH.
24. A rare genetic disorder called oculocutaneous albinism is caused by mutations in the tyrosinase gene.
25. A high intake of vitamin C can lead to increased tyrosinase activity and melanin production in the skin.
26. The tyrosinase enzyme is susceptible to oxidative damage.
27. Tyrosinase is involved in the formation of neuromelanin in the brain.
28. The expression of tyrosinase is controlled by a feedback mechanism involving melanin synthesis.
29. Tyrosinase-positive melanoma cells can be identified using immunohistochemistry.
30. Tyrosinase activity can also be inhibited by certain plant extracts and natural compounds.
31. Tyrosinase is an important biomarker in the diagnosis and treatment of melanoma.
32. Inhibition of tyrosinase activity is a common mechanism used in skin lightening products.
33. Tyrosinase is a member of the copper-containing oxidoreductase family of enzymes.
34. Certain drugs and chemicals can induce tyrosinase expression in melanoma cells.
35. Genetic variations in tyrosinase activity can contribute to individual differences in skin pigmentation.
36. Tyrosinase is involved in the synthesis of eumelanin and pheomelanin in the skin.
37. The study of tyrosinase regulation is important for understanding the mechanisms of skin pigmentation.
38. A low activity of tyrosinase is associated with increased risk of skin cancer.
39. Tyrosinase inhibitors have also been investigated as potential treatments for vitiligo.
40. The tyrosinase enzyme is the target of many natural and synthetic inhibitors for various applications.
Common Phases
1.
Tyrosinase is an enzyme that catalyzes the production of melanin in the skin;
2. Mutation in the
tyrosinase gene can lead to various skin disorders;
3.
Tyrosinase inhibitors are used in cosmetic products to lighten skin tone;
4.
Tyrosinase plays a vital role in the pigmentation of eyes, hair, and skin;
5. Research is being conducted on
tyrosinase inhibitors for potential use in treating certain types of cancer.