"Ectophosphodiesterases" Example Sentences
1. The activity of ectophosphodiesterases is crucial for maintaining the balance of extracellular nucleotides.
2. Ectophosphodiesterases are enzymes that hydrolyze phosphodiester bonds in extracellular nucleotides.
3. The expression of ectophosphodiesterases varies among different cell types and tissues.
4. Ectophosphodiesterases play a role in regulating cell signaling and immune response.
5. Increased levels of ectophosphodiesterases have been found in certain diseases such as cancer.
6. The function of ectophosphodiesterases is influenced by environmental factors such as temperature and pH.
7. Ectophosphodiesterases are involved in the breakdown of adenosine triphosphate (ATP) and other nucleotides.
8. The substrates of ectophosphodiesterases include cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP).
9. Ectophosphodiesterases are inhibited by certain drugs that target the intracellular phosphodiesterases.
10. Lack of ectophosphodiesterases activity can lead to abnormal cellular responses and pathological conditions.
11. There are several isoforms of ectophosphodiesterases that have distinct substrate specificities.
12. Ectophosphodiesterases are expressed on cell surfaces and in extracellular spaces.
13. The levels of ectophosphodiesterases can be increased by exposure to certain chemicals and drugs.
14. Ectophosphodiesterases prevent the accumulation of extracellular nucleotides that can cause cellular toxicity.
15. Certain pathological conditions are associated with decreased ectophosphodiesterases activity.
16. Ectophosphodiesterases are thought to play a role in the regulation of neurotransmitter release.
17. The activity of ectophosphodiesterases can be modulated by extracellular calcium and magnesium ions.
18. Ectophosphodiesterases belong to the family of phosphodiesterases that catalyze the hydrolysis of cyclic nucleotides.
19. Different tissues and organs have varying levels of ectophosphodiesterases activity.
20. Ectophosphodiesterases are important targets for the development of drugs for the treatment of certain diseases.
21. The regulation of ectophosphodiesterases activity is complex and involves multiple signaling pathways.
22. Ectophosphodiesterases are involved in the regulation of intracellular calcium signaling.
23. The expression of ectophosphodiesterases is regulated by transcription factors and epigenetic mechanisms.
24. Ectophosphodiesterases are important for the control of extracellular ATP levels in the central nervous system.
25. The activity of ectophosphodiesterases is modulated by endogenous inhibitors and activators.
26. Ectophosphodiesterases are involved in the regulation of inflammatory responses and immune cell activation.
27. The function of ectophosphodiesterases is important for the maintenance of tissue homeostasis.
28. Ectophosphodiesterases are expressed in a cell-specific manner and play distinct roles in various physiological processes.
29. The identification of new ectophosphodiesterases inhibitors has led to the development of novel therapeutic strategies.
30. Ectophosphodiesterases are important for the control of extracellular purinergic signaling.
Common Phases
1.
Ectophosphodiesterases play a crucial role in extracellular nucleotide metabolism;
2. The activity of
ectophosphodiesterases can be modulated by various factors;
3.
Ectophosphodiesterases have been implicated in a wide range of physiological and pathological processes;
4. Inhibition of
ectophosphodiesterases can have therapeutic potential in certain diseases;
5.
Ectophosphodiesterases have been studied extensively as potential therapeutic targets for cancer and cardiovascular diseases.