"Intronic" Example Sentences
1. Intronic mutations can have profound effects on gene expression.
2. The intronic region of the gene plays a crucial role in splicing.
3. An intronic variant may affect the function of non-coding RNA molecules.
4. Intronic sequence conservation can provide clues to gene regulation.
5. The presence of intronic repeats can contribute to gene instability.
6. A deletion in the intronic region can lead to alternative splicing.
7. Intronic enhancers can enhance gene expression independent of their location.
8. An intronic SNP may affect splicing efficiency or accuracy.
9. Intronic lncRNAs can modulate gene expression through chromatin remodeling.
10. A synonymous intronic SNP can affect mRNA stability or translation efficiency.
11. The intronic region may contain consensus sequences for splicing enhancers or silencers.
12. Aberrant splicing due to intronic mutations can cause inherited diseases.
13. An intronic variant may affect the binding of splicing factors or other regulatory proteins.
14. Intronic methylation can regulate splicing through binding of specific proteins.
15. The intronic region may contain microRNA binding sites that affect mRNA stability or translation.
16. Splice site mutations in the intronic region can result in exon skipping or inclusion.
17. A loss of intronic function due to mutations can affect mRNA processing or stability.
18. Intronic alternative polyadenylation can generate different mRNA isoforms.
19. Intronic mutations can disrupt the formation of ribonucleoprotein complexes required for splicing.
20. The intronic region may contain binding sites for RNA editing enzymes that affect mRNA structure or function.
21. Alternative splicing of intronic exons can generate protein isoforms with different functions.
22. Intronic antisense transcripts can regulate gene expression through epigenetic mechanisms.
23. An intronic SNP may affect the stability or localization of mRNA intron-containing complexes.
24. Intronic enhancers and silencers can modulate gene expression in a tissue-specific manner.
25. The intronic region may contain binding sites for miRNA target prediction algorithms.
26. Intronic mutations can disrupt splicing by altering RNA secondary structure or splicing motifs.
27. The intronic region may contain transcription factor binding sites that affect gene expression.
28. Intronic small nucleolar RNAs can guide posttranscriptional modifications to rRNA.
29. An intronic SNP may affect the frequency of exonic splicing regulatory elements or ESEs.
30. Intronic transcribed regions can act as lncRNAs that regulate gene expression in trans.
Common Phases
1. The
intronic region of the gene was found to contain unexpected mutations;
2. RNA sequencing data revealed extensive alternative splicing events in the
intronic regions;
3. The
intronic mutations were predicted to affect the proper splicing of the mRNA transcript;
4. The
intronic sequences were analyzed to identify potential binding sites for splicing factors;
5. The
intronic regions were highly conserved across multiple species, suggesting functional significance.