"Laminin" Example Sentences
1. Laminin is a protein component of the extracellular matrix.
2. The structure of laminin is vital for the integrity of tissue.
3. Mutations in the laminin gene can cause various genetic disorders.
4. Laminin is involved in cell adhesion and migration processes.
5. The binding of laminin to integrins on cell membranes is crucial for cellular interactions.
6. Laminin helps to support and maintain the structure of basement membranes.
7. The presence of laminin can signal to cells to proliferate or differentiate.
8. Laminin is a glycoprotein that is composed of three polypeptide chains.
9. Laminin alpha-5 chain is a specific isoform that is present in the developing brain.
10. Antibodies against laminin have been found in autoimmune diseases.
11. Laminin is a substrate for cell culture and tissue engineering.
12. The laminin network can influence the mechanical properties of tissues.
13. Laminin can interact with other extracellular matrix proteins such as collagen and fibronectin.
14. Laminin mutations have been linked to myopathy and kidney diseases.
15. The laminin beta-1 chain is necessary for formation of the neuromuscular junction.
16. Laminin is important for the development and regeneration of peripheral nerves.
17. Abnormal laminin expression can contribute to tumor progression and metastasis.
18. Laminin is found in many organs such as liver, skin, and lung.
19. Laminin is a target for therapeutic agents for various diseases.
20. The distribution of laminin varies between different tissues and organs.
21. Laminin plays a critical role in embryonic development and organogenesis.
22. Laminin can affect cell behavior such as survival and apoptosis.
23. Laminin knockout mice develop severe phenotypes and embryonic lethality.
24. The laminin alpha-1 chain has been implicated in Alzheimer's disease.
25. Laminin can be modified post-translationally to affect its function.
26. Laminin is a biomarker for certain cancers and tissue injury.
27. Laminin has been used in regenerative medicine to repair damaged tissues.
28. Laminin is a key component in the pathogenesis of certain autoimmune diseases.
29. Laminin has been studied extensively in the context of cell migration and invasion.
30. The anti-adhesive properties of laminin can block tumor cell invasion.
Common Phases
1.
Laminin is a glycoprotein that is found in the extracellular matrix of many tissues.
2. Research has shown that
laminin is important for cell adhesion and differentiation.
3. The structure of
laminin resembles a cross, with three arms that bind to other molecules in the extracellular matrix.
4. Mutations in
laminin genes have been linked to various diseases, such as muscular dystrophy and kidney disorders.
5.
Laminin has also been used in tissue engineering and regenerative medicine applications.
6. Scientists continue to study the role of
laminin in development, physiology, and disease.