"Pepsinogen" Example Sentences
1. Pepsinogen is a precursor to the digestive enzyme pepsin.
2. The stomach produces pepsinogen in response to food intake.
3. The proteolytic activity of pepsinogen is activated by stomach acid.
4. A lack of pepsinogen production can lead to digestive problems.
5. Pepsinogen is secreted by chief cells in the gastric glands.
6. Pepsinogen secretion is regulated by hormone signals from the brain and digestive tract.
7. Pepsinogen levels may be monitored to diagnose certain medical conditions.
8. The presence of pepsinogen in the stomach can indicate adequate gastric function.
9. Pepsinogen synthesis is stimulated by the amino acid histidine.
10. Inhibiting the production of pepsinogen can reduce acid reflux symptoms.
11. Pepsinogen is converted to pepsin by the enzyme HCl.
12. Pepsinogen is inactive until it is cleaved at specific sites within the molecule.
13. Elevated levels of pepsinogen may indicate gastric inflammation or cancer.
14. The pH of the stomach can affect the activation of pepsinogen.
15. Pepsinogen is one of several enzymes involved in protein digestion.
16. Pepsinogen is stored in vesicles within the chief cells.
17. The function of pepsinogen in the digestive process is essential.
18. Some dietary supplements contain pepsinogen as a digestive aid.
19. The genetic expression of pepsinogen varies among individuals.
20. Reduced pepsinogen secretion may be a side effect of certain medications.
21. The measurement of pepsinogen can be used to diagnose gastric ulcers.
22. Chronic alcohol consumption can lead to decreased pepsinogen synthesis.
23. The release of pepsinogen is regulated by a negative feedback loop.
24. Pepsinogen secretion increases during gastric distention.
25. Infants have lower levels of pepsinogen than adults.
26. The pH optimum for pepsinogen activity is around 2.0.
27. Degradation of pepsinogen in the stomach can lead to autoimmune disorders.
28. Pepsinogen secretion is stimulated by the neurotransmitter acetylcholine.
29. Inhibiting the conversion of pepsinogen to pepsin can reduce stomach irritation.
30. Pepsinogen levels can fluctuate with changes in diet and lifestyle.
Common Phases
1.
Pepsinogen is a precursor enzyme, secreted by chief cells in the stomach;
2. It is converted into an active enzyme, pepsin, by the acidic environment in the stomach;
3.
Pepsinogen levels can be used as a marker for gastric function and digestive health;
4. Low levels of
pepsinogen have been associated with an increased risk of gastric cancer;
5.
Pepsinogen is involved in breaking down protein molecules into smaller peptides and amino acids;
6. In some cases, medications can be used to stimulate
pepsinogen secretion and improve digestive function.