"Podosomal" Example Sentences
1. The podosomal adhesions of the cells were responsible for their migration.
2. The podosomal machinery is essential for the invasion of cancer cells.
3. The formation of podosomal adhesions requires the recruitment of several proteins.
4. The podosomal activity of macrophages plays a crucial role in tissue remodeling.
5. The podosomal ring is composed of actin filaments and contractile proteins.
6. The disruption of podosomal adhesions impairs cell migration and invasion.
7. The podosomal signaling pathway is activated by integrin engagement.
8. The podosomal matrix contains several enzymes that modify the extracellular matrix.
9. The podosomal phenotype of cells is influenced by extracellular cues and signaling pathways.
10. The regulation of podosomal activity is mediated by small GTPases and kinase cascades.
11. The turnover of podosomal adhesions is influenced by matrix stiffness and elasticity.
12. The podosomal cytoskeleton is composed of microfilaments, intermediate filaments, and microtubules.
13. The role of podosomal adhesions in cancer metastasis is well documented.
14. The formation of podosomal adhesions is initiated by the clustering of integrin receptors.
15. The podosomal response of cells to environmental cues is crucial for their survival and function.
16. The podosomal proteome is characterized by a high turnover rate and protein diversity.
17. The dynamic turnover of podosomal adhesions is regulated by the actin cytoskeleton and myosin motors.
18. The podosomal machinery is involved in the phagocytosis of pathogens by immune cells.
19. The podosomal adhesions of endothelial cells are essential for the formation of blood vessels.
20. The coordinated activity of podosomal machinery and signaling pathways is required for cell migration.
21. The podosomal assembly of macrophages is influenced by the presence of bacterial pathogens.
22. The podosomal remodeling of the extracellular matrix is important for tissue repair and regeneration.
23. The disruption of podosomal activity leads to cellular dysfunction and disease.
24. The podosomal matrix is enriched with enzymes that degrade and remodel the extracellular matrix.
25. The assembly of podosomal adhesions requires the recruitment of several cytoskeletal and signaling proteins.
26. The podosomal activity of immune cells is regulated by cytokines and chemokines.
27. The formation of podosomal adhesions requires the activation of focal adhesion kinase and other signaling kinases.
28. The podosomal organization of cells is influenced by their interactions with the extracellular environment and neighboring cells.
29. The podosomal machinery is important for the transendothelial migration of leukocytes.
30. The podosomal activity of cancer cells is regulated by the expression of oncogenes and tumor suppressors.
Common Phases
1.
Podosomal organization is essential for cell migration;
2.
Podosomal proteins mediate adhesion to and degradation of extracellular matrix;
3.
Podosomal dynamics play a role in invasion of cancer cells;
4.
Podosomal signaling regulates gene expression and cell behavior;
5.
Podosomal formation is induced by extracellular stimuli;
6.
Podosomal turnover is crucial for cell adhesion and migration.