"Replicase" Example Sentences
1. The replicase enzyme is essential for the replication of viral RNA.
2. Some viruses have a proofreading function in their replicase enzyme, which helps prevent errors in RNA replication.
3. The replicase complex is composed of multiple proteins working together to replicate RNA.
4. Scientists are currently studying the structure and function of replicase enzymes to develop antiviral drugs.
5. The SARS-CoV-2 virus uses its replicase enzyme to replicate its RNA genome inside human cells.
6. Mutations in the replicase gene of coronaviruses can affect their virulence and ability to spread between hosts.
7. Some viruses, such as poliovirus, have an RNA-dependent RNA polymerase (replicase) that can directly synthesize new RNA strands.
8. The interaction between host factors and viral replicase enzymes plays an important role in determining the outcome of viral infections.
9. Replicase inhibitors are a promising class of antiviral drugs that target the virus's ability to replicate.
10. The use of broad-spectrum replicase inhibitors may help combat emerging viral diseases with unknown mechanisms of replication.
11. The replicase of hepatitis C virus is a target for antiviral therapy, as it is essential for viral replication.
12. The replicase of SARS-CoV-2 is a source of viral RNA mutations that can alter the virus's behavior and transmission.
13. The replicase complex of positive-strand RNA viruses, such as Zika virus, can form membrane-bound structures called replication factories.
14. One strategy for preventing viral replication is to target the host proteins that interact with viral replicases.
15. The use of RNA interference (RNAi) to target viral replicase genes shows promise as a therapeutic approach for viral infections.
16. The replicase machinery of retroviruses, such as HIV, includes a reverse transcriptase that converts viral RNA into DNA.
17. Vaccines that target the replicase of RNA viruses may be able to stimulate an immune response against multiple strains of the virus.
18. The replicase of influenza viruses is a rapidly evolving target for antiviral drugs due to the high mutation rate of the virus.
19. The interaction between viral replicases and host cell membranes is an important component of the viral replication cycle.
20. Mutations in the replicase of the measles virus can lead to changes in the virus's behavior and its ability to evade the immune system.
21. The replicase of coronavirus is highly sensitive to a class of antiviral drugs called nucleoside analogs.
22. The use of protease inhibitors in combination with replicase inhibitors has been shown to improve the efficacy of antiviral therapy.
23. The complex interplay between viral replicases and host cell signaling pathways is an area of active research.
24. The replicase of the Ebola virus is a promising target for vaccine development, as it is conserved across multiple strains of the virus.
25. In RNA viruses, the replicase machinery is often associated with viral RNA fragments called replication intermediates.
26. The replicase complex of hepatitis B virus is a multifunctional enzyme that plays a role in both RNA transcription and DNA replication.
27. The use of structural information to design inhibitors that specifically target viral replicases is a promising strategy for antiviral drug development.
28. The replicase of the herpes simplex virus is responsible for the synthesis of viral DNA during infection.
29. Some coronaviruses, such as SARS-CoV-2, have evolved strategies to evade host immune responses that target their replicase.
30. The replicase machinery of some RNA viruses can induce the formation of cytoplasmic granules called stress granules, which play a role in cellular stress response.
Common Phases
1. The
replicase enzyme synthesizes viral RNA;
2. The high fidelity
replicase complex enables efficient replication of DNA;
3.
Replicase-mediated RNA synthesis is pivotal in generating new viral particles;
4. The malfunction of
replicase can result in mutations and genetic disorders.