"Transcriptase" Example Sentences
1. The HIV virus uses reverse transcriptase to convert its RNA into DNA inside infected cells.
2. The process of transcription requires RNA polymerase and other transcriptase enzymes.
3. Without the proper function of reverse transcriptase, some retroviruses cannot infect their host cells.
4. The accuracy of RNA transcription can be influenced by the activity of transcriptional factors and transcriptase enzymes.
5. By altering the activity of reverse transcriptase, researchers can develop new therapies to target retroviruses like HIV.
6. Reverse transcriptase inhibitors have been developed to block the activity of the enzyme in order to treat viral infections.
7. Some RNA viruses use a variety of transcriptase enzymes to replicate their genome, which can make them difficult to target with drugs.
8. There are different types of transcriptase enzymes that can be used in gene expression studies, including T7 polymerase and SP6 polymerase.
9. Transcriptional activity can be monitored in real-time using fluorescent reporter molecules that are activated by transcriptase enzymes.
10. Inaccurate transcription can lead to mutations and genetic disorders, highlighting the importance of properly functioning transcriptase enzymes.
11. The use of transcriptase enzymes in molecular biology has revolutionized the study of gene expression and regulation.
12. Reverse transcriptase is also used in certain laboratory techniques, such as the creation of cDNA from RNA samples.
13. Some retroviruses have evolved to become resistant to reverse transcriptase inhibitors, highlighting the need for continued research in this area.
14. By analyzing changes in transcriptase activity over time, researchers can gain insight into the dynamics of RNA transcription in living cells.
15. Some RNA viruses encode their own reverse transcriptase enzymes, allowing them to replicate their genome without relying on host cell machinery.
16. The accuracy of transcription can be influenced by a variety of factors, including the quality of the RNA sample being used, the activity of transcription factors, and the efficiency of the transcriptase enzyme being used.
17. In order for reverse transcriptase inhibitors to be effective, they must be able to penetrate the cell membrane and reach the site of viral replication.
18. The development of new transcriptase inhibitors is an active area of research, due to the increasing prevalence of drug-resistant viruses.
19. The activity of reverse transcriptase can be monitored using a variety of biochemical assays and imaging techniques.
20. Some RNA viruses, such as influenza, use a combination of host cell machinery and viral transcriptase enzymes to replicate their genome.
21. Transcriptase activity can be modulated through the use of expression plasmids and other genetic techniques.
22. Reverse transcriptase is one of the four main types of enzymes used by retroviruses to replicate their genome.
23. The activity of transcriptase enzymes can be controlled through a variety of mechanisms, including post-translational modifications and feedback loops.
24. The use of reverse transcriptase in genetic engineering has enabled the creation of synthetic genes and other molecular constructs.
25. Some retroviruses, such as the human T-cell leukemia virus, have evolved to use a modified form of reverse transcriptase that is highly resistant to inhibitors.
26. The efficiency of transcription can be influenced by a variety of environmental factors, such as pH and temperature, as well as the activity of other cellular enzymes.
27. Transcriptase inhibitors have been shown to be effective in treating a variety of retroviral infections, including HIV and hepatitis B virus.
28. The high error rate of reverse transcriptase can lead to the generation of genetic diversity and the evolution of new viral strains over time.
29. Transcriptase activity is tightly regulated by a variety of mechanisms, including the formation of protein complexes and the binding of small molecule moderators.
30. The use of transcriptase enzymes in molecular diagnostics has enabled the development of highly sensitive and accurate tests for detecting viral infections.
Common Phases
1. The viral
transcriptase was successfully inhibited.
2. The reverse
transcriptase enzyme is critical for HIV replication.
3. The development of a new
transcriptase inhibitor is underway.
4. The RNA
transcriptase produces complementary DNA strands.
5. The RNA polymerase acts as a
transcriptase during transcription.
6. The reverse
transcriptase converts RNA to DNA.
7. The
transcriptase activity was measured using a colorimetric assay.
8. The
transcriptase complex is composed of multiple subunits.
9. The transcription of viral genes requires viral
transcriptase.
10. The inhibition of reverse
transcriptase is an important component of HIV treatment.