"Axoneme" Example Sentences
1. The axoneme is a microtubule-based structure that forms the core of the flagella.
2. The 9+2 arrangement of microtubules is a characteristic feature of the axoneme in eukaryotic flagella.
3. Axonemes are involved in the movement of cilia and flagella, which are essential for the motility of cells.
4. The dynein arms attached to the microtubules of the axoneme generate the force that drives the movement of cilia and flagella.
5. Mutations in axonemal genes can cause defects in cilia and flagella, resulting in ciliopathies.
6. The axoneme plays a crucial role in the sensing of mechanical and chemical stimuli by cilia and flagella.
7. The structure of the axoneme is conserved across different species, from protozoans to mammals.
8. The axoneme contains several accessory proteins and enzymes that regulate the assembly and disassembly of the microtubules.
9. The axoneme is composed of several different types of microtubules, including A, B, and C tubules.
10. The central pair of microtubules in the axoneme is important for the coordination of ciliary and flagellar movements.
11. The architecture of the axoneme is critical for its function, as different lengths and diameters of the microtubules can affect the bending and twisting of cilia and flagella.
12. The axoneme has a distal end that terminates in the axonemal cap, which is important for the coordination of ciliary and flagellar movements.
13. The axoneme is anchored to the basal body, which serves as the docking site for the attachment of the cilia and flagella to the cytoskeleton.
14. The axoneme is composed of tubulin, a protein that forms the building blocks of microtubules.
15. The axoneme is also involved in the regulation of cell signaling pathways, particularly those that activate ciliary and flagellar movements.
16. The axoneme is enriched in several signaling and scaffolding proteins, including polycystin-2, a protein mutated in polycystic kidney disease.
17. The axoneme is a dynamic structure that undergoes constant turnover, with microtubules being added and removed from the core.
18. The axoneme is involved in a variety of physiological processes, including sperm motility, mucociliary clearance, and sensory transduction.
19. The axoneme is negatively regulated by several proteins, such as NPHP4, that play a role in maintaining the stability and integrity of cilia and flagella.
20. The axoneme is highly conserved across different tissues and organs, suggesting that it plays an important role in organogenesis and tissue development.
21. The axoneme is involved in directional sensing by cilia and flagella, allowing them to respond to gradients of chemical and physical stimuli.
22. The axoneme is regulated by several signaling pathways, such as the Wnt and Hedgehog pathways, that play a role in cell fate and tissue patterning.
23. The axoneme is essential for the proper alignment and orientation of cilia and flagella, which is critical for their function.
24. The axoneme is involved in the sensing of light by photoreceptor cells, allowing them to respond to changes in illumination.
25. The axoneme is a dynamic structure that can adapt to changes in the environment, such as changes in temperature and pH.
26. The axoneme is involved in the migration of cells, particularly during development and wound healing.
27. The axoneme is enriched in several proteins that play a role in cytoskeletal organization and dynamics, such as centrin and hydin.
28. The axoneme is a potential therapeutic target for the treatment of ciliopathies, such as primary ciliary dyskinesia and cystic kidney disease.
29. The axoneme is a complex structure that is still not fully understood, with many questions remaining about its assembly, regulation, and function.
30. The axoneme is an important target for future research into cilia and flagella biology, with potential applications in biotechnology and medicine.
Common Phases
1. The
axoneme is a microtubule-based structure;
2. The
axoneme plays a critical role in motility;
3. The
axoneme is found in cilia and flagella;
4. The
axoneme is composed of nine microtubule doublets arranged in a ring;
5. The
axoneme uses ATP to generate movement;
6. The
axoneme is crucial for the transport of fluids and particles;
7. The
axoneme is involved in the clearance of bacteria and debris from the respiratory system;
8. The
axoneme is also important for gamete motility in reproductive systems;
9. The
axoneme is a key component in the movement of the embryonic node in early development;
10. The structure of the
axoneme is highly conserved across species.