"Exons" Example Sentences
1. The exons in this gene are critical for its function.
2. Mutations in the exons can cause various diseases.
3. Alternative splicing can result in different combinations of exons in the mRNA.
4. The exon junction complex is involved in mRNA processing.
5. The exons are the coding regions of the gene.
6. The presence of introns can affect the arrangement of exons in the final mRNA.
7. The exon-intron structure is conserved across evolutionarily diverse species.
8. Some genes have multiple exons that can be spliced in different ways.
9. The size and number of exons can vary greatly between genes.
10. The discovery of exons and introns revolutionized our understanding of eukaryotic gene structure.
11. The identification of exons can aid in gene annotation and functional analysis.
12. Exon skipping is a strategy being explored for the treatment of certain genetic diseases.
13. The human genome contains approximately 180,000 exons.
14. The splicing of exons is tightly regulated and can be influenced by various factors.
15. Mutations in exons can affect protein structure and function.
16. The exons are transcribed into pre-mRNA, which is then processed to mature mRNA.
17. Some exons can be alternatively spliced to produce multiple protein isoforms.
18. The coding sequence of exons is ultimately translated into amino acid sequences.
19. The presence of exons is one of the features that distinguishes eukaryotic genes from prokaryotic genes.
20. Exon shuffling, whereby exons are exchanged between genes, can result in the evolution of new proteins.
21. The order of exons within a gene can be important for proper splicing and protein function.
22. Some exons are highly conserved across different species, indicating their importance for gene function.
23. Incomplete splicing of exons can result in the production of truncated or non-functional proteins.
24. The correct splicing of exons is essential for normal development and physiology.
25. The exonuclease enzyme is involved in the removal of nucleotides from the end of DNA or RNA molecules.
26. Some disease-causing mutations affect the splicing of exons and can lead to abnormal protein production.
27. The discovery of exons and introns represented a major breakthrough in molecular biology.
28. The presence of exons and introns can complicate gene therapy approaches for certain diseases.
29. Exonuclease activity is important for DNA repair and maintenance of genome integrity.
30. The elimination of introns and preservation of exons is a crucial step in the processing of pre-mRNA.
Common Phases
1. The
exons are the coding regions of DNA; they contain the necessary information for protein synthesis.
2. Mutations in
exons can lead to genetic diseases; they might disrupt the reading frame of the gene.
3. Alternative splicing can result in different protein variants; it involves selectively removing certain
exons during RNA processing.
4. Intron retention can also occur during splicing; it happens when an intron is not properly removed, leading to an abnormal mRNA molecule with introns and
exons.
5. Exon skipping is a potential therapy for genetic diseases; it involves selectively skipping a mutated exon during splicing to restore the correct reading frame of the gene.