Fibril example sentences

"Fibril" Example Sentences

1. Nerve fibers are composed of fibrils.
2. Muscle fibrils contract to cause muscle movement.
3. Collagen fibrils give strength and structure to tissues and organs.
4. The axon is surrounded by neurofibrils.
5. Microfibrils make up the cellulose microfibril layer of plant cell walls.
6. Microtubules are composed of fibril subunits.
7. Fibrils form the twisted rope-like structure of amyloid plaques.
8. Microfibrils provide rigidity to the cell walls of plant cells.
9. Fibrils give tendons their strength and elasticity.
10. Neurofibrils transport nerve impulses along the axon.
11. Actin fibrils enable muscle contraction.
12. Keratin fibrils form the protein matrix of hair and nails.
13. Microfibrils are made of cellulose and hemicellulose.
14. The elongation and shortening of fibrils causes muscle contraction and relaxation.
15. Neurofilaments are fibrils found within neurons.
16. Interfibrillar compounds separate collagen fibrils.
17. Microfibrils align along the direction of tensile stress within plant tissues.
18. Microtubule-associated proteins bind to the outer surface of microtubule fibrils.
19. Collagen fibrils give strength, flexibility and resilience to tendons and ligaments.
20. Protein fibrils are characterized by a cross beta sheet structure and insolubility.
21. Actin fibrils slide past each other to enable muscle shortening.
22. Elastin fibrils allow certain tissues to stretch and recoil.
23. Microfibrils maintain cell shape and mechanical strength in plant cells.
24. Neurofibrils transmit nerve impulses along the axon to reach the synapse.
25. Chitin fibrils provide structure and protection to the exoskeleton of arthropods.
26. Fibrils are composed of bundled fibrils or protofibrils.
27. Fibril-associated glycoproteins weave among collagen fibrils.
28. During mitosis, microtubule fibrils form the mitotic spindle.
29. Amyloid fibrils are associated with neurodegenerative diseases.
30. Hemidesmosome fibrils anchor epithelial cells to the basement membrane.
31. Intermediate filament fibrils provide mechanical stability within the cytoskeleton.
32. Fibronectin fibrils form a network that cells can adhere to.
33. Microtubule fibrils form the rail network that chromosomes move along during cell division.
34. Microfibrils align parallel to the axis of cell elongation in plants.
35. Interfibrillar matrix surrounds collagen fibrils.
36. Proteoglycan aggregates anchor collagen fibrils to each other.
37. Cortical microtubule fibrils regulate cellulose deposition in plant cells.
38. Keratin intermediate filament fibrils form the protein meshwork of hair and nails.
39. Actin fibrils slide over myosin crossbridges to generate muscle force.
40. Microtubule-associated proteins regulate the assembly and stability of microtubule fibrils.
41. Collagen fibrillogenesis involves the assembly of collagen monomers into fibrils.
42. The polarity of microtubule fibrils determines their dynamic instability.
43. Microtubule fibrils create tracks for molecular motor proteins to walk along.
44. Fibronectin fibrils promote cell adhesion through integrin binding.
45. Bradykinin induces relaxation of elastin fibrils within blood vessels.
46. Fibrils become established in a particular direction based on mechanical stresses.
47. Fibroblasts deposit collagen fibrils to form the extracellular matrix.
48. Axonemal fibrils help whip-like structures called flagella generate movement.
49. Fibrils form a highly organized three-dimensional scaffold within ECM.
50. Self-assembly of fibrils involves non-covalent interactions and conformational changes.

Common Phases

1. Microtubules and neurofilaments are formed from bundles of fibrils organized in parallel arrays.
2. The fibrils of collagen give connective tissue strength and elasticity.
3. Amyloid fibrils are associated with Alzheimer's disease and other neurodegenerative disorders.
4. Aggregates of amyloid fibrils can build up in the brain, interfering with neuronal function.
5. The amyloid fibril plaques found in the brains of Alzheimer's patients contain abnormally folded amyloid beta protein.
6. Scientists are studying how amyloid fibrils form and accumulate with the hope of developing new treatments for Alzheimer's.
7. The cytoskeleton of eukaryotic cells consists of three types of fibrils: microtubules, actin filaments, and intermediate filaments.
8. Microtubule fibrils are assembled from tubulin proteins.
9. Actin filaments are fibrils composed of actin monomers.
10. Keratin intermediate filaments provide mechanical strength and resistance to stress within cells.
11. Muscle cells contain elongated actin and myosin fibrils that slide past each other, allowing for contraction.
12. Interstitial fibrils form a framework that supports the structure of connective tissues.
13. The collagen fibrils of tendons connect muscle to bone.
14. Elastic fibrils allow tissues like skin and blood vessels to stretch and retract.
15. Neurofilaments and microtubules together make up the cytoskeleton of axons in neurons.
16. Muscle fibrils become shorter and thicker during muscle atrophy.
17. Protein aggregation results in the formation of insoluble protein fibrils and amyloid fibrils.
18. Fibril formation is a characteristic feature of many neurodegenerative diseases.
19. Scientists are studying how proteins misfold and aggregate to better understand fibril formation.
20. Microglia become activated in response to the presence of amyloid fibrils and neuronal damage.
21. Brain trauma and brain lesions can lead to abnormal tau fibril formation.
22. Tau fibrils accumulate inside neural cells forming neurofibrillary tangles, a hallmark of Alzheimer's disease.
23. Fragmented axonal fibrils may occur after traumatic brain or spinal cord injury.
24. Crosslinking agents can be used to stabilize collagen fibrils for use in tissue engineering applications.
25. Vitamin C promotes the formation of collagen fibrils that are stronger and more stable.
26. Magnetically aligned fibrils can be used to guide the growth of neurons and other cells.
27. Pharmacological compounds that inhibit fibril formation are being investigated for potential neuroprotective effects.
28. Transmission electron microscopy can be used to visualize individual amyloid fibrils and determine their morphology.
29. At high concentrations, insulin forms fibrils that can precipitate out of solution.
30. Fibril forming proteins contain regions that are prone to adopt beta sheet structures.
31. Branched fibrils form when multiple filaments associate laterally.
32. Immunohistochemistry stains can be used to detect the presence of fibrils in tissue sections.
33. Heat shock proteins may inhibit protein aggregation by binding to partially folded intermediates and preventing fibril formation.
34. Disrupting hydrogen bonds within fibrils can halt their growth and proliferation.
35. Scientists are working to develop fibril disrupting molecules that could be used as future therapeutics.
36. Chaperone proteins may help degrade fibrils by unravelling their structures.
37. Fibril structure can be characterized using atomic force microscopy.
38. Certain strains of bacteria produce extracellular protein fibrils known as curli.
39. Shorter fibrils tend to aggregate more quickly than longer fibrils due to higher surface area to volume ratios.
40. Cryo-electron microscopy is being used to visualize the structure of amyloid fibrils at high resolution.
41. Cytoskeletal fibrils help maintain cell shape, polarity and mechanical integrity.
42. Heating samples can induce protein fibrils to unfold and dissociate back into monomers.
43. Solid-state NMR spectroscopy provides information about conformation and packing of proteins within fibrils.
44. Fibril forming propensities vary among different proteins and protein isoforms.
45. Transgenic animal models are used to study fibril formation in vivo.
46. Fibrils usually grow by laterally incorporating soluble proteins.
47. Chemical modifications can disrupt hydrophobic interactions that stabilize fibril structures.
48. Competitive inhibitors can bind to fibrils and prevent them from elongating.
49. Fibrils tend to be insoluble and resistant to proteolytic degradation.
50. Thioflavin T dye selectively binds to amyloid fibrils and is commonly used to detect their presence.
51. Some microorganisms produce crosslinked extracellular fibrils that provide structural support.
52. Fibril formation generally follows a nucleation-polymerization mechanism.
53. Modified proteins that are prone to forming fibrils can be used as markers for certain disease states.
54. Fibrils often form elongated, unbranched structures with high aspect ratios.
55. Mechanisms that disrupt fibril elongation may help slow the progression of neurodegenerative diseases.
56. Scientists are working to develop anti-fibril antibodies for diagnostic and therapeutic applications.
57. Crystalline fibril structures can diffract X-rays, enabling their 3D structure to be determined.
58. Breakdown products of degenerating fibrils may activate microglia and immune cells in the brain.
59. Fibrous proteins contain amino acid sequences that promote alignment of polypeptide chains into fibrils.
60. Mutations that enhance fibril formation are associated with familial forms of some neurodegenerative disorders.