Ubiquitylases example sentences
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Related (2): ubiquitination, deubiquitinases
"Ubiquitylases" Example Sentences
- Ubiquitylases play a crucial role in regulating protein degradation.
- The ubiquitylases gene is highly conserved across species.
- Targeting ubiquitylases could be a potential therapeutic strategy for cancer.
- Ubiquitylases are responsible for attaching ubiquitin to proteins.
- The number of ubiquitylases in the human genome is estimated to be around 600.
- Defects in ubiquitylases have been linked to neurodegenerative diseases.
- Certain viruses can hijack ubiquitylases to evade the host immune response.
- Ubiquitylases are involved in numerous cellular processes, including DNA repair and cell signaling.
- The ubiquitylase family consists of several subfamilies, such as RING and HECT.
- The identification of novel ubiquitylases could provide new insights into protein regulation.
- The activity of ubiquitylases can be regulated by post-translational modifications.
- Some ubiquitylases can target specific substrates for degradation.
- Ubiquitylases can form multi-protein complexes with other enzymes and regulators.
- The expression of ubiquitylases can be dysregulated in certain cancers.
- Mutations in ubiquitylase genes can lead to inherited disorders, such as Fanconi anemia.
- The development of specific inhibitors for ubiquitylases could be a promising therapeutic approach.
- Ubiquitylase activity can be regulated by allosteric mechanisms.
- Scientists are still working to understand the full range of functions of ubiquitylases.
- A better understanding of ubiquitylase biology could aid in the development of precision medicine.
- Ubiquitylases that regulate cell cycle progression are of particular interest to cancer researchers.
- Some drugs currently used in cancer treatment work by inhibiting the activity of ubiquitylases.
- The activity of ubiquitylases has been linked to aging and age-related diseases.
- Ubiquitylases are involved in the quality control of proteins in the endoplasmic reticulum.
- The study of ubiquitylases has led to the discovery of numerous other regulatory enzymes and pathways.
- Defects in the ubiquitin-proteasome system, including ubiquitylases, have been implicated in Parkinson’s disease.
- Ubiquitylase inhibitors have also shown potential in treating viral infections.
- The regulation of ubiquitylase activity is a complex and dynamic process.
- The discovery of new ubiquitylases has opened up new avenues for research in protein regulation.
- Certain ubiquitylase genes are frequently mutated in various types of cancer.
- The ubiquitin-proteasome system, which includes ubiquitylases, is a critical pathway for maintaining cellular homeostasis.
Common Phrases
- Ubiquitylases play a crucial role in regulating cellular functions;
- They are responsible for tagging specific proteins for degradation;
- Ubiquitylation is essential for maintaining protein turnover and preventing buildup of damaged proteins;
- Defects in ubiquitylation can lead to a variety of diseases;
- Ubiquitylases can be targeted with drugs to treat certain cancers;
- The discovery of ubiquitylation has revolutionized the field of protein regulation.
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